Prenatal Exposure to Alcohol Reduces Nephron Number and Raises Blood Pressure in Progeny

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Fetal Programming Prenatal Dexamethasone Exposure Does Not Alter Blood Pressure and Nephron Number in the Young Adult Marmoset Monkey

The influence of prenatal factors on the development of arterial hypertension has gained considerable interest in recent years. Prenatal dexamethasone exposure was found to induce hypertension and to alter nephron number and size in rodents and sheep. However, it is not clear whether these findings are applicable to nonhuman primates. Thus, we examined the effects of prenatal dexamethasone trea...

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Prenatal Exposure to Alcohol

Fetal Alcohol Syndrome (FAS) is a set of birth defects caused by maternal consumption of alcohol during pregnancy. At birth, children with FAS can be recognized by growth deficiency and a characteristic set of minor facial traits that tend to become more normal as the child matures. Less evident at birth—but far more devastating to FAS children and their families—are the lifelong effects of alc...

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Prenatal Exposure to Alcohol

Maternal alcohol consumption during pregnancy can cause serious birth defects, of which fetal alcohol syndrome (FAS) is the most devastating. Recognizable by characteristic craniofacial abnormalities and growth deficiency, this condition includes severe alcohol-induced damage to the developing brain. FAS children experience deficits in intellectual functioning; difficulties in learning, memory,...

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Association between Prenatal Lead Exposure and Blood Pressure in Children

BACKGROUND Lead exposure in adults is associated with hypertension. Altered prenatal nutrition is associated with subsequent risks of adult hypertension, but little is known about whether prenatal exposure to toxicants, such as lead, may also confer such risks. OBJECTIVES We investigated the relationship of prenatal lead exposure and blood pressure (BP) in 7- to 15-year-old boys and girls. ...

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ژورنال

عنوان ژورنال: Journal of the American Society of Nephrology

سال: 2010

ISSN: 1046-6673,1533-3450

DOI: 10.1681/asn.2010040368